Leucoderma Treatment, Causes, Symptoms and Treatments

Leucoderma Treatment, Causes, Symptoms and Treatments

Leucoderma is a dermatological disorder in which patches of skin lose their natural color, resulting in irregular white patches that can appear on various parts of the body. It occurs due to the destruction of melanocytes, the cells responsible for producing the pigment melanin. Although the exact cause of vitiligo remains elusive, researchers believe that it involves a combination of genetic, autoimmune, and environmental factors.

Table of Content:

What is Leucoderma (Vitiligo)?

Leucoderma, also known as vitiligo, is a skin disorder characterized by the loss of pigmentation in certain areas of the skin. This condition occurs when the cells responsible for producing melanin, the pigment that gives color to the skin, hair, and eyes, are destroyed. As a result, white patches of varying sizes and shapes appear on the skin, causing not only a change in appearance but also potential emotional and psychological distress.

Types of Leucoderma

There are a few different types of leucoderma based on various factors such as the distribution of the patches, the progression of the disease, and its associated features. Here are some common types:

Non-segmental Vitiligo: This is the most common type of vitiligo, where depigmented patches appear symmetrically on both sides of the body. These patches often appear on areas exposed to sunlight, such as the face, hands, arms, and feet. Non-segmental vitiligo can further be categorized into subtypes:

  • Generalized Vitiligo: Patches are distributed widely across the body.
  • Acrofacial Vitiligo: Patches are concentrated on the extremities (hands and feet) and around the face.
  • Universal Vitiligo: Nearly complete depigmentation of the skin, covering a significant portion of the body.

Segmental Vitiligo: This type of vitiligo involves the appearance of depigmented patches on one side or a specific segment of the body. It usually starts at an early age and progresses for a limited period before stabilizing.

Mixed Vitiligo: This type is a combination of both non-segmental and segmental vitiligo, where individuals exhibit patches on both sides of the body as well as in specific segments.

Focal Vitiligo: In this type, only a few small patches appear on isolated areas of the body.

Mucosal Vitiligo: This type affects the mucous membranes (such as the inside of the mouth and genital area) and often occurs alongside other forms of vitiligo.

Trichrome Vitiligo: In this type, the depigmented patches show three distinct colors - white, light brown, and normal skin color.

It's important to note that the categorization of vitiligo into different types may vary among medical professionals, and new insights into the condition might lead to updates in classification. If you suspect you have vitiligo or are seeking more information, it's best to consult with a dermatologist or a healthcare professional who can provide an accurate diagnosis and guidance.

Vitiligo Causes and Prevention

Vitiligo is a complex skin disorder with multifactorial origins. Several variables influence its growth, including:

Genetic Predisposition: A strong genetic component plays a pivotal role in the manifestation of vitiligo. Research indicates that individuals with a family history of the condition are more susceptible to its onset. Certain genetic variations disrupt the functioning of melanocytes, the cells responsible for producing skin pigment.

Autoimmune Dysfunction: An autoimmune response, wherein the body's immune system attacks its own melanocytes, is a significant contributor to vitiligo. This disrupts the melanin production process, leading to depigmentation. Addressing autoimmune factors is vital for managing vitiligo.

Oxidative Stress: Oxidative stress, caused by an imbalance between free radicals and antioxidants in the body, can trigger vitiligo. This stress damages melanocytes and impedes melanin synthesis. Minimizing oxidative stress through a balanced diet and lifestyle modifications can be beneficial.

Effective Prevention Strategies

While complete prevention may not always be possible, adopting certain strategies can help reduce the risk of vitiligo or slow its progression:

Sun Protection: Exposure to the sun's ultraviolet (UV) rays can exacerbate vitiligo. UV rays can harm sensitive skin areas and hinder repigmentation efforts. Regularly applying broad-spectrum sunscreen and wearing protective clothing can shield the skin from UV damage.

Balanced Diet: A nutritious diet rich in vitamins and minerals, particularly antioxidants, can support skin health. Incorporate foods like fruits, vegetables, nuts, and whole grains. These nutrients combat oxidative stress and contribute to overall well-being.

Manage Stress: Chronic stress can aggravate autoimmune responses and trigger vitiligo flare-ups. Practicing stress-reduction techniques such as yoga, meditation, and deep breathing can help manage stress and promote skin health.

Topical Treatments: Various topical treatments, such as corticosteroid creams and calcineurin inhibitors, can help manage vitiligo symptoms. Consult a dermatologist to identify the best treatment plan for your specific needs.

Leucoderma Symptoms: Recognizing the Signs

Depigmented Patches: The emergence of depigmented or white patches on the skin is the major symptom of vitiligo. These patches are often more noticeable in individuals with darker skin tones. They can occur on any part of the body, including the face, hands, feet, and even inside the mouth.

Symmetrical Distribution: Vitiligo often exhibits a symmetrical pattern, meaning that if a patch appears on one side of the body, a similar patch may appear on the corresponding area of the opposite side. This symmetrical distribution is a hallmark of the condition and aids in its diagnosis.

Segmental Vitiligo: In some cases, vitiligo may follow a segmental pattern, affecting only one side or a segment of the body. This type of vitiligo is usually seen in younger individuals and might progress more rapidly than the generalized form.

Premature Graying of Hair: Another noticeable symptom is the premature graying of hair on the scalp, eyebrows, eyelashes, and other body areas with affected skin. This occurs due to the loss of melanin-producing cells in these regions.

Psychological Impact: The emotional and psychological impact of vitiligo should not be underestimated. Individuals with vitiligo might experience lowered self-esteem, anxiety, and depression due to the visible changes in their appearance. Addressing these aspects through counseling and support groups is essential for holistic management.

Is Vitiligo Curable?

The question of whether vitiligo is curable has long been a subject of debate in the medical community. While there is currently no definitive cure that can guarantee the complete restoration of pigmentation in all cases, various treatment options aim to manage the condition and potentially induce repigmentation.

How to Cure Vitiligo in a Month?

While a complete cure for vitiligo within a month might be a challenging goal, several treatment approaches can help manage the condition and promote repigmentation over time. It's important to note that the effectiveness of these approaches can vary from person to person, and results may take longer than a month to become noticeable.

Topical Treatments: Topical corticosteroids, calcineurin inhibitors, and vitamin D analogs are commonly prescribed to stimulate repigmentation in affected areas. These treatments work by reducing inflammation and encouraging the production of melanin.

Phototherapy: Phototherapy involves exposing the skin to ultraviolet (UV) light, either in the form of UVB or UVA radiation. Narrowband UVB therapy is often effective in stimulating repigmentation, although it may require multiple sessions over several weeks.

Surgical Interventions: In cases where other treatments have not yielded satisfactory results, surgical options like autologous melanocyte transplantation, suction blister grafting, and microskin grafting can be considered. These treatments entail moving melanocytes from unaffected areas to depigmented patches.

Depigmentation: In situations where a large portion of the skin is affected, depigmentation of the remaining pigmented areas might be considered to achieve a more uniform appearance.


While a complete and universal cure for vitiligo remains elusive, significant strides have been made in the field of dermatology to manage the condition and promote repigmentation. Various treatment options, including topical creams, phototherapy, and surgical interventions, offer hope to those affected by vitiligo. It's important for individuals with vitiligo to consult with a qualified dermatologist to determine the most suitable treatment plan based on their specific condition and needs. Remember, managing vitiligo is a journey that requires patience, perseverance, and professional guidance.

Frequently Asked Questions (Leucoderma Treatment)

Q1: What is leucoderma?
Leucoderma, also known as vitiligo, is a skin disorder characterized by the loss of pigmentation, leading to white patches on the skin.

Q2: Is leucoderma treatable?
While there is no definitive cure for leucoderma, various treatments can help manage the condition and improve pigmentation.

Q3: What are the common treatment options for leucoderma?
Common treatment options include topical corticosteroids, phototherapy, excimer laser, depigmentation, and surgical procedures.

Q4: How do topical corticosteroids work in leucoderma treatment?
To minimize inflammation and promote repigmentation, topical corticosteroids are administered directly to the afflicted skin areas.

Q5: What is phototherapy for leucoderma?
Phototherapy involves exposing the skin to UVB light to stimulate melanocyte activity and promote pigmentation in the white patches.

Q6: How does the excimer laser help in treating leucoderma?
The excimer laser delivers targeted UVB light to affected skin areas, promoting repigmentation by stimulating melanocyte production.

Q7: What is depigmentation treatment used for?
Depigmentation involves lightening the remaining pigmented skin to match the white patches, usually considered when the condition is widespread.

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About Author

Dr. Nisha Sharma

Studied at Red Roses Sr. Sec. School, D-Block, Arya Samaj Mandir; she has established herself into a renowned personality. She received her degrees (both BDS and MDS) in dentistry. She received her fellowship at the Pierre Fauchard Academy (FPFA). She has also received her certifications for full mouth rehabilitation and cosmetic dentistry. Currently, she practices her medicine of dentistry at Dr. Chopra Dental Clinic in Ramesh Nagar, Delhi.

Comments ( 1)

  • Mansi

    Thanks for the valuable information.

    2023-01-05 00:00:00

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